Redefining hope

for patients with glioblastoma

mission

Glioblastoma (GBM) remains one of the most aggressive and lethal cancers, with a median survival of only 15 months and no therapeutic progress in over two decades.

The challenge lies in its immunosuppressive tumor microenvironment, dominated by myeloid cells that exhaust T-cell function and promote tumor growth.

Technology

GlioCART addresses the key barriers in glioblastoma – immunosuppression and antigen escape – through its dual-action CAR-T therapy, targeting not only tumor cells but also reprogramming tumor-supporting myeloid cells into active immune effectors.

Our vision is to extend the reach of CAR-T therapy beyond hematologic malignancies, unlocking durable efficacy in solid tumors, starting with glioblastoma and expanding into other myeloid-driven cancers.

Market Opportunity

Global IP protection strategy:

– Exclusive worldwide rights to the license (University of Basel)
– PCT national phase entered in major jurisdictions

Team and Execution

Dieter Willmann

CEO
Serial entrepreneur and
experienced company builder

Prof. Dr. Gregor Hutter

CMO
Professor of Neurosurgery
clinical lead of the trial

Dr. Patrice Zeis

COO
Operations, strategy &
company development

Dr. Valerio Sabatino

CSO
R&D platform
Portfolio expansion